logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name rno-miR-133b
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods H&E staining, immunohistochemistry, cells transfection, luciferase reporter assay, MTT assay, flow cytometry, qRT-PCR, Western blot
Expression pattern down-regulated
Functional description Overexpression of miR-133b and AGT silencing promoted proliferation of vascular endothelial cells, while inhibiting the process of vascular endothelial cell apoptosis.
PubMed ID 29488353
Year 2018
Title Effects of microRNA-133b on retinal vascular endothelial cell proliferation and apoptosis through angiotensinogen-mediated angiotensin II- extracellular signal-regulated kinase 1/2 signalling pathway in rats with diabetic retinopathy.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.