ncRNA name | rno-miR-133b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | H&E staining, immunohistochemistry, cells transfection, luciferase reporter assay, MTT assay, flow cytometry, qRT-PCR, Western blot |
Expression pattern | down-regulated |
Functional description | Overexpression of miR-133b and AGT silencing promoted proliferation of vascular endothelial cells, while inhibiting the process of vascular endothelial cell apoptosis. |
PubMed ID | 29488353 |
Year | 2018 |
Title | Effects of microRNA-133b on retinal vascular endothelial cell proliferation and apoptosis through angiotensinogen-mediated angiotensin II- extracellular signal-regulated kinase 1/2 signalling pathway in rats with diabetic retinopathy. |
Drug-related ncRNA | NO |
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